1,3-dicarbonyl compounds and process for their preparation

Details 1,3-dicarbonyl compounds and process for their preparation 1,3-dicarbonyl compounds and process for their preparation

C - Chemistry, Metallurgy

07

C

260/518, 260/582

C07C 49/00 (2006.01) C07C 69/757 (2006.01) C07C 177/00 (1980.01)

Patent

CA 1105484

ABSTRACT OF THE DISCLOSURE 1,3-Dicarbonyl compounds and process for their preparation of the general formula Image wherein R1 represents an alkyl group of 1 to 12 carbon atoms, which may be substituted by a hydroxyl group; R2 and R4 represent a hydrogen atom; R3 represents a hydrogen atom or an alkyl group of 1 to 12 carbon atoms, which may be substituted by a hydroxyl group; RA represents an alkyl group of 1 to 12 carbon atoms or a phenyl group, each of which may be substituted by a carboxyl or lower alkoxycarbonyl group; and RB represents an alkyl. alkenyl or alkynyl group, each of which has up to 12 carbon atoms and may be sub- stituted by a hydroxyl group; and R1 and R3 may additionally together represent an alkylene group of 2 to 4 carbon atoms, which may be substituted by a hydroxyl group. These compounds, particularly those derived from cyclopentanone and cyclohexanone have hypotensive activity.

221362

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