Arylaminoimidazoline derivatives and the preparation thereof

C - Chemistry – Metallurgy – 07 – D

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260/314.8

C07D 233/50 (2006.01) C07D 233/38 (2006.01)

Patent

CA 1107285

Abstract of Disclosure Novel Arylaminoimidazoline derivatives of the formulas Image in which R1 and X2 are halogen or an alkyl group with 1 to 4 C atoms, R3 is hydrogen or an alkyl radical with 1 - 4 C atoms and n and m each represent an integer from 1 to 3, the sum of n + m being an integer from 2 to 5 inclusive, and their salts are prepared by reacting 2-arylamino-2-imidazolines of the formulas Image in which R1 and R2 are defined as above, with active amides or anhydrides of a cycloaliphatic carboxylic acid of the formula Image , in which R3, n and m are defined as above. This novel compounds have a pronounced analgesic action. O.Z.647/B

317503

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