Process for the preparation of solutions of 7-...

Details Process for the preparation of solutions of 7-... Process for the preparation of solutions of 7-...

C - Chemistry, Metallurgy

07

D

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C07D 501/18 (2006.01) A61K 31/545 (2006.01) C07D 501/04 (2006.01) C07D 501/06 (2006.01) C07D 501/57 (2006.01)

Patent

CA 1173824

ABSTRACT OF THE DISCLOSURE A process for the preparation of solutions of 7-amino- cephalosporanic acids wherein there is obtained a salt of the general formula III: Image where R1 may be a group selected from among hydrogen, methyl, or a low molecular weight alkoxy, R2 is a group selected from among methyl, methoxy, azido, chlorine, carbamoylmethyl acetoxy, thiomethyl, phenylthiomethyl and others, x means from 3 to 5 carbon atoms and y means from 2 to 4 carbon atoms is disclosed. The process is based on the reaction of a compound of formula I Image with a bicyclic amidine. 1.

390705

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