C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 215/60 (2006.01) A61K 31/135 (2006.01)
Patent
CA 2116685
(-)-Ritodrine, that is (-)-erythro-1-(p- hydroxyphenyl)-2-[2-(p-hydroxyphenyl)ethylamino)-1- propanol or a salt thereof substantially free from the (+)-isomer is disclosed. The compound has a strong suppressive effect on uterine contraction in comparison with (~)-ritodrine and (+)-ritodrine and has the same level of toxicity as these compounds, so that it can be used as a therapeutic agent of threatened premature birth and threatened abortion as well as a therapeutic agent of dysmenorrhea having a high safety.
Fukuda Yoshimasa
Kosugi Isao
Niizato Tetsutarou
Shibazaki Yoshiaki
Yamazaki Naoki
Fetherstonhaugh & Co.
Meiji Seika Kabushiki Kaisha
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