Method of indicating rheumatoid factors

Details Method of indicating rheumatoid factors Method of indicating rheumatoid factors

G - Physics

01

N

150/11

G01N 33/48 (2006.01) G01N 33/564 (2006.01) G01N 33/72 (2006.01) G01N 33/80 (2006.01) G01N 33/86 (2006.01) G01N 33/96 (2006.01)

Patent

CA 1098014

ABSTRACT OF THE DISCLOSURE A method of indicating rheumatoid factors, primarily such rheumatoid factors which belong to other immunoglobulin classes than the immunoglobulin class IgM, in an aqueous sample is disclosed. According to this method the sample is reacted in the presence of the complement factor C1q in non- bound form with soluble, aggregated immunoglobulin labelled with one or more analytically indicatable atoms or groups to selectively precipitate such rheumatoid factors which, in the presence of C1q, are able to precipitate aggregated immuno- globulin, whereafter the analytically indicatable atoms or groups are indicated in the precipitation phase and/or in the solution. -2-

283448

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