Preparation of substituted 2-aminopyrazines

Details Preparation of substituted 2-aminopyrazines Preparation of substituted 2-aminopyrazines

C - Chemistry, Metallurgy

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C07D 241/20 (2006.01) C07C 17/35 (2006.01) C07C 29/40 (2006.01) C07C 33/20 (2006.01)

Patent

CA 1157860

X-4616 -1- Abstract of the Disclosure A process for the preparation of substituted 2-aminopyrazines by reaction of an .alpha.-chloro or .alpha.-bromo oxime with an aminoacetonitrile in the presence of an acid-uptake agent, followed by separation of the inter- mediate novel hydroxyimino-substituted aminoaceto- nitrile, and cyclization thereof with acid.

349061

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