Process for the preparation of a [d-.alpha.-amido-(p-...

Details Process for the preparation of a [d-.alpha.-amido-(p-... Process for the preparation of a [d-.alpha.-amido-(p-...

C - Chemistry, Metallurgy

07

D

260/104.5, 260/1

C07D 499/68 (2006.01) C07D 499/12 (2006.01) C07D 501/06 (2006.01) C07D 501/20 (2006.01)

Patent

CA 1111413

ABSTRACT A process for the preparation of a penicillanic acid or a cephalosporanic acid derivative containing a [D-.alpha.- amino-p-hydroxy phenyl-acetamido] group which comprises acylation of an appropriate silylated derivative of a 6- APA or 7-ACA compound, at a relatively low temperature, with an acylating agent derived from p-hydroxyphenyl gly- cine.

310665

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