Preparation process of acetamide derivatives with...

C - Chemistry – Metallurgy – 07 – D

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260/552.1, 260/5

C07D 295/14 (2006.01) C07D 295/13 (2006.01)

Patent

CA 1091679

A B S T R A C T Novel acetamides of the general formula: Image wherein each of rings a and b may optionally be substituted by one or more of the groups F, Cl, Br, CF3. NO2, NH2, C1-4alkyl, C1-4alkoxy And methylenedioxy; Z is Image or Image ; and A is hydrogen, C1-4alkyl, C1-4hydroxyalkyl or a group of the formula R1R2N-Y- in which Y is a divalent linear or branched chain C1-4hydrocarbon radical, and either R1 and R2 are the same of different and are each hydrogen or C1-4alkyl or NR1R2 is a heterocyclic group which has five to seven ring members including, optionally, 4 second heteroatom such as N or O, and which may be substituted; and the addition salts of the compounds wherein A is a basic group. These novel acetamides are useful on the central nervous system.

299865

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