Diagnostic devices and method for immuno-chemical...

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G01N 31/22 (2006.01) A61K 39/44 (2006.01) G01N 33/48 (2006.01) G01N 33/543 (2006.01)

Patent

CA 1074228

ABSTRACT OF THE DISCLOSURE A diagnostic device for immuno-chemical quantification includes a capillary-containing, porous carrier, e.g., a strip of cellulose fibre, starch polyvinyl chloride or polyvinyl chloride-silica, with antibodies bound thereto by adsorption or covalent bonding. Immuno-chemical quantification is effected by a method involving adding a sample containing an antigen to be quantified to the device, initiating a capillary migration, and effecting an assay of antigen-containing areas of the device by the addition of antibodies bound to a color indicator, e.g. a fluorescent compound such as fluoresceine isocyanate or an enzyme capable of catalyzing a color-developing reaction.

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