Triazoloquinazolinone derivatives

Details Triazoloquinazolinone derivatives Triazoloquinazolinone derivatives

C - Chemistry, Metallurgy

07

D

260/242.01

C07D 487/04 (2006.01) C07D 239/95 (2006.01)

Patent

CA 1156228

ABSTRACT OF THE DISCLOSURE: Process for preparing compounds of general formula I Image (I) wherein X represents a hydrogen or a halogen atom or a nitro, trifluoromethyl, methyl or methoxy radical; n is 2, 3, 4 or 5; and R1 and R2, which may be the same or different, each represents a hydrogen atom or a Cl 5 alkyl or hydroxyalkyl radical or, together with the nitrogen atom to which they are attached, they represent a saturated heterocyclic ring selected from the group consisting of pyrrolidino, piperidino, morpholi- no and piperazino ring optionally being substituted by one or more substituents selected from hydroxy, Cl-5 alkyl, Cl-5 hydro- xyalkyl, C3-6 cycloalkyl, Cl-5 acyl, C2-6 alkoxycarbonyl and phenyl radicals (said phenyl radical itself being optionally substituted by a halogen atom or a trifluoromethyl radical); and acid addition salts thereof, having remarkable antihistaminic and bronchospasmolytic activity.

370869

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