C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/314, 260/310
C07D 233/64 (2006.01) C07D 233/54 (2006.01) C07D 277/24 (2006.01) C07D 277/26 (2006.01)
Patent
CA 1075700
ABSTRACT OF THE DISCLOSURE Compounds are disclosed of the formula Image wherein Het is an imidazole or thiazole ring optionally substituted by lower alky and R is hydrogen or a lower alkyl group and phar- maceutically acceptable salts thereof. These compounds have histamine H2-receptor antagonist activity and useful as inhibitors of histamine stimulated gastric acid secretion.
273246
Durant Graham J.
Ganellin Charon R.
Young Rodney C.
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