Poloxamer-iodine gel

Details Poloxamer-iodine gel Poloxamer-iodine gel

A - Human Necessities

61

K

167/4.2

A61K 33/18 (2006.01) A01N 25/00 (2006.01) A01N 25/04 (2006.01) A01N 59/12 (2006.01) A61K 47/48 (2006.01)

Patent

CA 1051776

POLOXAMER-IODINE GEL Abstract of the Disclosure A poloxamer-iodine gel composition adapted for use as a topical germicide is provided by combining with an aqueous iodide-iodine solution, preferably containing a compatible buffering agent, a polyoxyethylene- polyoxypropylene block polymer in which the polyoxypropylene hydrophobic block has a molecular weight of about 3500 to 4500, and the molecular weight of the polymer is about 11,000-12,000, in an amount to comprise about 20 to 30% by weight of the gel composition. The gel composition may contain 0.25 to 2% of elemental iodine, and 0.25 to 2% of iodide (I-), with the I-:I2 ratio being in excess of 0.25:1; and a compatible buffering agent, such as a citrate, preferably comprising about 0.2 to 1.0%, of the gel composition. S P E C I F I C A T I O N

232731

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