Method for the preparation of avirulent viral mutant from...

Details Method for the preparation of avirulent viral mutant from... Method for the preparation of avirulent viral mutant from...

A - Human Necessities

61

K

167/130

A61K 39/12 (2006.01) A61K 39/245 (2006.01) C12N 7/06 (2006.01) C12N 15/01 (2006.01)

Patent

CA 1069821

ABSTRACT OF THE DISCLOSURE The present invention relates to the preparation of an avirulent viral mutant from the Aujeszky's virus which consists in reacting the nucleus of said virus, containing desoxyribonucleic acid, with the antimetabolite 5-iodine-2- desoxyuridin and after the eighth passage into a predetermined culture medium, there is obtained an apathogentic and immuno- genic mutant to be used as a live vaccine.

281836

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