Pharmaceutical compositions

Details Pharmaceutical compositions Pharmaceutical compositions

C - Chemistry, Metallurgy

07

D

260/353, 260/208

C07D 317/66 (2006.01) C07D 213/53 (2006.01) C07D 295/12 (2006.01) C07D 295/13 (2006.01)

Patent

CA 1060438

A B S T R A C T A pharmaceutical composition comprises a pharmaceutical carrier or diluent together with a compound of the formula: (I) Image in which: R1 is a hydrogen atom or a lower alkyl group; R2 and R3 are the same or are different and each is is a hydrogen or halogen atom, a hydroxy group, or a lower alkoxy group, or R2 and R3 are attached to adjacent carbon atoms on the benzene nucleus A and together represent a carboxyclic ring fused to benzene nucleus A; R4 is a hydrogen atom an alkyl or aralkyl group, or a substituted or unsubstituted aryl group, or R4 together with R3 forms a non-aromatic ring fused to benzene nucleus A which non- aromatic ring may itself have further rings fused thereto, R5 is a hydrogen atom, a lower alkyl group, a lower hydroxyalkyl group, or a carboxylic acid group; R6 is a carbon-carbon or carbon-hydrogen bond, a methylene (-CH2-) group, a hydroxymethylene (-CHOH-) group, or a mercaptomeihylene (-CHSH) group; and R7 is a hydrogen atom, an alkyl or substituted alkyl group, an aryl or substituted arly group, or a heterocyclic or substituted heterocyclic group.

225873

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