Amination process

Details Amination process Amination process

C - Chemistry, Metallurgy

07

D

260/296, 260/394

C07D 401/04 (2006.01) C07D 213/72 (2006.01) C07D 213/73 (2006.01) C07D 213/74 (2006.01) C07D 295/00 (2006.01)

Patent

CA 1054604

ABSTRACT OF THE DISCLOSURE A process for the preparation of aminopyridines of the formula Image wherein R1 and R2 are identical or different and are hydrogen or lower alkyl or, together with the nitrogen atom to which they are attached, form a 5-, 6-, or 7-membered heterocyclic ring containing up to 2 more hetero atoms, comprises reacting 4-pyridylpyridinium chloride or a salt thereof, at an elevated temperature, with an acid amide of the formula Image ABSTRACT OF THE DISCLOSURE - continued wherein R1 and R2 are as above and Z is -CO-R3 wherein R3 is hydrogen, lower alkyl, Image or Image and R4 and R5 are hydrogen or lower alkyl.

263609

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