Derivatives of indole active on the cardiovascular system

Details Derivatives of indole active on the cardiovascular system Derivatives of indole active on the cardiovascular system

C - Chemistry, Metallurgy

07

D

260/319, 260/306

C07D 209/14 (2006.01) C07D 209/16 (2006.01)

Patent

CA 1161849

ABSTRACT OF THE DISCLOSURE The present invention relates to the chemical products of general formula: Image .I. in which R1 and R2 designate hydrogen; halogen, lower alkyl or lower alkoxy; R3 and R4 designate hydrogen, alkyl, alkoxy, halogen, nitro, acyl, alkylthio, alkylsulfinyl, alkylsulfonyl, a (CH2)nCOOR, (CH2)2CONHR, (CH2)nNHCOOR or (CH2)nNHCOR group; or R3 and R4 together form a heterocycle bonded to the benzene cycle; X1 is hydrogen, alkyl, hydroxymethyl or COOR and X2 is hydrogen or methyl; and to the pharmaceutically acceptable salts of said products. It also relates to a process for preparing said products and to the drugs active in particular on the cardiovascular system, containing at least one of said products.

359075

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