Process for 3-chloro cephalosporins

Details Process for 3-chloro cephalosporins Process for 3-chloro cephalosporins

C - Chemistry, Metallurgy

07

D

260/101.5

C07D 501/20 (2006.01) A61K 31/545 (2006.01) C07D 501/04 (2006.01) C07D 501/59 (2006.01) C07D 501/60 (2006.01)

Patent

CA 1099256

Abstract of the Disclosure This invention provides a novel process whereby 7.beta.-acylamino-3-hydroxy-3-cephem-4-carboxylic acid ester sulfoxides are chlorinated and reduced in a single step with a halogenating reagent in dimethylformamide to provide 7.beta.-acylamino-3-chloro-3-cephem-4-carboxylic acid ester sulfides.

282954

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