C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/280.2
C07D 401/04 (2006.01) C07D 207/18 (2006.01) C07D 213/04 (2006.01)
Patent
CA 1093559
RAN 4002/20 Abstract Disclosed are pyrrolidine compounds of the general formula Image I wherein R1 represents a pyridyl group, R2 represents a hydrogen atom or a lower alkyl group, R3 represents a hydrogen atom or a lower alkyl or benzyl group and R4 represents a phenyl group which may carry one or more substituents selected from halogen, lower alkyl, lower alkoxy, nitro and amino, and acid addition salts thereof, as well as a process for the manufacture of these substances, which have analgesic activity. Also disclosed are the intermediate pyrroline compounds of the formula III Image (III)
338111
Bernauer Karl
Pfoertner Karlheinz
Schmid Hans
Schneider Fernand
Gowling Lafleur Henderson Llp
Hoffmann-La Roche Limited
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