Pyrido[1,2-a]pyrimidine derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/505 (2006.01)

Patent

CA 1269103

PYRIDO[1,2-a]PYRIMIDINE DERIVATIVES ABSTRACT OF THE DISCLOSURE Pyrido[1,2-a]pyrimidine derivatives of the general formula [I] and their physiologically acceptable salts are provided: [I] Image where R is a hydrogen atom, a halogen atom or a methyl group, and n is a whole number of 0, 1 or 2. The pyrido[1,2-a]- pyrimidine derivatives and their salts exhibit an excellent antagonistic effect on slow-reacting substance of anaphylaxis and, therefore, are useable for the treatment of allergic diseases.

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