Substituted dihydroquinolone carboxylic acids and...

C - Chemistry – Metallurgy – 07 – D

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C07D 215/56 (2006.01) A61K 31/395 (2006.01) C07D 405/04 (2006.01) C07D 405/10 (2006.01) C07D 498/06 (2006.01) C07F 7/18 (2006.01)

Patent

CA 1262249

SUBSTITUTED DIHYDROQUINOLONE CARBOXYLIC ACIDS AND ANTI-BACTERIAL COMPOSITIONS CONTAINING T~EM Abstract 1-Substituted-6-fluoxo-7-aryl-(8-fluoro)-1,4- dihydroquinol-4-one 3-carboxylic acids having anti- bacterial activity. They may be prepared by reacting the corresponding alkyl 1-substituted-6-fluoro-7- bromo-(8-fluoro)-1,4-dihydroquinol-4-one-3-carboxylate with an arylmetallic compound and hydrolyzing the ester formed.

496861

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