Process for the manufacture of p-hydroxyphenylacetic acid

C - Chemistry – Metallurgy – 07 – C

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260/516.6

C07C 59/52 (2006.01) C07C 51/377 (2006.01)

Patent

CA 1170271

HOE 80/F 007 PROCESS FOR THE MANUFACTURE OF p-HYDROXYPHENYL- ACETIC ACID Abstract of the disclosure p-Hydroxyphenylacetic acid is prepared by reduction of p-hydroxymandelic acid with HI in the presence of red phos- phorus. According to a preferred embodiment, the reaction is carried out in one vessel in which the mandelic acid is prepared in situ from phenol and glyoxylic acid.

368741

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