Recombinant hosts

Details Recombinant hosts Recombinant hosts

C - Chemistry, Metallurgy

12

N

195/1.29, 195/1.

C12N 15/71 (2006.01) C07K 14/52 (2006.01) C12N 1/20 (2006.01) C12N 15/11 (2006.01)

Patent

CA 1338664

A genomically modified host is provided wherein a regulatable promoter is more effectively induced due to inefficient production of an aporepressor-activator. The same regulatable promoter is then used on recombinant expression vectors transformed into the host for recombinant protein production. This results in higher levels of expression of the desired recombinantly produced protein. A specific aspect of the invention is shown in Fig. 1.

504577

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