Preparation of n-((1- naphthalenyl)thioxomethyl)glycine...

A - Human Necessities – 61 – K

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260/508.5

A61K 31/265 (2006.01)

Patent

CA 1188322

ABSTRACT OF THE DISCLOSURE N-[(1-Naphthalenyl)thioxomethyl]glycine derivatives are prepared by thionaphthoylation of glycine derivatives. These derivatives are inhibitors of aldose reductase. They are therefore useful for treating diabetic complications for example neuropathy, nephro- pathy, retinopathy cataracts and atherosclerosis.

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