Synthesis of dioxabicylo (3.2.1)octanes and oxepanes

Details Synthesis of dioxabicylo (3.2.1)octanes and oxepanes Synthesis of dioxabicylo (3.2.1)octanes and oxepanes

C - Chemistry, Metallurgy

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C07D 313/04 (2006.01) C07C 45/51 (2006.01) C07D 303/32 (2006.01) C07D 307/20 (2006.01) C07D 493/08 (2006.01) C07F 7/18 (2006.01)

Patent

CA 1171422

ORTH 379 Synthesis of Dioxabicyclo[3.2.1]Octanes and Oxepanes ABSTRACT The synthesis of C-4 alkyl analogs of racemic (IRS,4SR,5RS)-4-(4,8-dimethyl-5-hydroxy-7-nonenyl)-4- methyl 3,8-dioxabicyclo[3.2.1]octane-l-acetic acid and the corresponding (lRS,4RS,5RS)- derivative is described. The dioxabicyclo[3.2.1]octanes are useful as contragestational agents. The intermediate oxepane analogs are useful as intermediates in the preparation of the contragestational agent zoapatanol.

382365

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