Process for the preparation of azetidinones

Details Process for the preparation of azetidinones Process for the preparation of azetidinones

C - Chemistry, Metallurgy

07

D

260/335.5

C07D 205/08 (2006.01) C07D 499/88 (2006.01) C07F 7/10 (2006.01)

Patent

CA 1252471

ABSTRACT Azetidinones are prepared by cleaving the thiazolidine ring of a penam using an acyl or aroyl nitrate followed by treatment with an organic base. The resulting azetidinones are intermediates in the preparation of antibacterially active penems.

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