Pharmaceutical compositions for the treatment of occlusive...

A - Human Necessities – 61 – K

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A61K 31/445 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01)

Patent

CA 1313500

- 1 - Abstract Pharmaceutical Compositions for the Treatment of Occlusive Vascular Diseases The use is described of both (i) [1R-[1.alpha.(Z), 2.beta., 3.beta., 5.alpha.]]-(+)-7-[5-[[(1,1'-biphenyl)-4-yl]methoxy]-3-hydroxy-2-(1- piperidinyl)cyclopentyl]-4-heptenoic acid or a physiologically acceptable salt or solvate thereof and (ii) a thromboxane synthase inhibitor, either separately or in combination in the therapy or prophylaxis of occlusive vascular diseases in humans. Pharmaceutical compositions containing both (i) and (ii) are also described.

544010

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