Thiadiazole guanidines

Details Thiadiazole guanidines Thiadiazole guanidines

C - Chemistry, Metallurgy

07

D

167/234, 260/308

C07D 285/135 (2006.01) A61K 31/425 (2006.01)

Patent

CA 1320491

25448-44 ABSTRACT OF THE DISCLOSURE Thiadiazole guanidines of formula 1 Image 1 wherein R is hydrogen or C1-4 alkyl and their non-toxic salts are provided. The thiadiazole guanidines exhibit anticonvulsant activity and are indicated for use in the treatment of epilepsy. Processes for the preparation containing the thiadiazole guanidines and pharmaceutical compositions containing them are also provided.

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