Methods and compositions for chromosome specific staining

Details Methods and compositions for chromosome specific staining Methods and compositions for chromosome specific staining

C - Chemistry, Metallurgy

12

Q

150/5, 150/8.5

C12Q 1/68 (2006.01) G01N 1/30 (2006.01) G01N 33/52 (2006.01) G01N 33/58 (2006.01)

Patent

CA 1301605

METHODS AND COMPOSITIONS FOR CHROMOSOME SPECIFIC STAINING ABSTRACT OF THE DISCLOSURE Methods and compositions for chromosome-specific staining are provided. Compositions comprise heterogenous mixtures of labeled nucleic acid fragments having substantially complementary base sequences to unique sequence regions of the chromosomal DNA for which their associated staining reagent is specific. Methods include methods for making the chromosome-specific staining compositions of the invention, and methods for applying the staining compositions to chromosomes.

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