Method for the immunization of animals and men against...

A - Human Necessities – 61 – K

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A61K 39/002 (2006.01)

Patent

CA 1236399

METHOD FOR THE IMMUNIZATION OF ANIMALS AND MEN AGAINST TOXOPLASMA GONDII Abstract of the Disclosure A method for the immunization of mammals (including man) and birds, against Toxoplasma gondii is described which involves subcutaneous administration of a live, low-virulent vaccine comprising a temperature-sensitive mutant of the persistent, virulent RH strain of T. gondii. The vaccine gives immunity against subsequent chal- lenge, but does not persist and does not cause chronic infection of the subject and which there- fore cannot result in illness or death in the event that the subject later becomes immunosup- pressed.

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