Antimicrobial n-¬1-(alkyl or arylmethyl)-4(1h)-...

Details Antimicrobial n-¬1-(alkyl or arylmethyl)-4(1h)-... Antimicrobial n-¬1-(alkyl or arylmethyl)-4(1h)-...

C - Chemistry, Metallurgy

07

D

167/228, 260/294

C07D 213/74 (2006.01) A01N 43/40 (2006.01) A61K 31/44 (2006.01)

Patent

CA 1260943

ABSTRACT OF THE DISCLOSURE N-[1-(alkyl or arylmethyl)-4(1H)-pyridinylidine]- alkanamine and pharmaceutically acceptable acid addition salts thereof, for example, N-(1-octyl-4(1H)-pyridinylidine)- octanamine monohydrochloride salt, which are useful as antimicrobial agents, especially on living tissues and nonliving surfaces and most especially against pathogenic dental microbes, and a process for preparation, methods of use and compositions thereof are disclosed.

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