Phosphinylcycloalkylcarbonyl and...

Details Phosphinylcycloalkylcarbonyl and... Phosphinylcycloalkylcarbonyl and...

C - Chemistry, Metallurgy

07

K

167/103.05, 530/

C07K 5/06 (2006.01) A61K 31/675 (2006.01) C07K 5/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1316630

HA 415 ABSTRACT Compounds of the formula Image and their pharmaceutically acceptable salts wherein Z completes a cycloalkyl ring, a substituted cycloalkyl ring, a cycloalkenyl ring, a substituted cycloalkeny ring or a saturated heteroalkyl ring; R2 is lower alkyl, aralkyl or aminoalkyl and X is an amino or imino acid. The compounds possess angiotensin converting enzyme inhibition activity.

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