Preparation process of alpha-l-aspartyl-l-phenylalanine...

Details Preparation process of alpha-l-aspartyl-l-phenylalanine... Preparation process of alpha-l-aspartyl-l-phenylalanine...

C - Chemistry, Metallurgy

07

K

530/5.06

C07K 5/06 (2006.01) A23L 1/236 (2006.01) C07K 5/075 (2006.01)

Patent

CA 1278400

ABSTRACT The present invention relates to a process for preparing .alpha.-L-aspartyl-L-phenylalanine methyl ester or its hydrochloride. .alpha.-L-aspartyl-L-phenylalanine methyl ester or its hydrochloride is prepared by a process comprising: condensating N-formyl-L-aspastic acid anhydride and L-phenylalanine in water or in water containing methanol at a pH in the range of 7 - 12 to form N-formyl-.alpha.-L- aspartyl-L-phenylalanine; acidifying the reaction mixture successively with hydrochloric acid in the presence of methanol without isolating the N-formyl-.alpha.-L-aspartyl-L- phenylalanine so as to bring it into contact with hydrochloric acid in the presence of methanol for reaction and thereby to deposit .alpha.-L-aspartyl-L-phenylalanine methyl ester hydrochloride; separating the .alpha.-L-aspartyl-L- phenylalanine methyl ester hydrochloride; and neutraliz- ing said hydrochloride as required.

503684

Affiliated with

Also associated with

Rating

Preparation process of alpha-l-aspartyl-l-phenylalanine... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Preparation process of alpha-l-aspartyl-l-phenylalanine..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation process of alpha-l-aspartyl-l-phenylalanine... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1175111