Lipid derivatives, their production and use

Details Lipid derivatives, their production and use Lipid derivatives, their production and use

C - Chemistry, Metallurgy

07

C

167/179, 260/258

C07C 271/12 (2006.01) C07C 275/50 (2006.01) C07C 275/60 (2006.01) C07D 207/09 (2006.01) C07D 209/48 (2006.01) C07D 211/56 (2006.01) C07D 213/20 (2006.01) C07D 213/40 (2006.01) C07D 213/75 (2006.01) C07D 233/72 (2006.01) C07D 239/54 (2006.01) C07D 277/22 (2006.01) C07D 277/28 (2006.01) C07D 277/30 (2006.01) C07D 295/088 (2006.01) C07D 295/13 (2006.01) C07D 295/205 (2006.01) C07D 295/215 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 417/06 (2006.01) C07D 417/12 (2006.01) C07

Patent

CA 1281324

Abstract Novel lipid derivatives of the formula Image [wherein R1 is alkyl or alkylcarbamoyl; R2 is hydrogen, hydroxy which may be substituted, amino which may be substituted or cyclic amino; R3 is a chemical binding or alkylene which may be substituted; R4 is hydrogen, alkyl or aralkyl; X and Y are independently O, S or an imino group which may be substituted, and when Y is an imino group, Y, together with the imino group represented by X or R4, may form a ring; and Z is imino or a nitrogen-containing heterocyclic ring which may be substituted] and salts thereof have inhibiting activity on platelet activating factor and are useful as a preventive or therapeutic agent for a variety of circulatory-diseases and allergic disorders and also as an antineoplastic agent.

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