Process for purifying growth hormone-like materials

Details Process for purifying growth hormone-like materials Process for purifying growth hormone-like materials

C - Chemistry, Metallurgy

07

K

530/3.12

C07K 14/61 (2006.01)

Patent

CA 1253997

Abstract A process is provided for separating impur- ities from an impure mixture containing growth hormone- like material, which comprises: (1) applying said mixture to a reverse phase macroporous acrylate ester copolymer resin support at a pH of from about 7 to about 9; and (2) eluting said growth hormone-like material from said support with an aqueous eluant having a pH of from about 7 to about 9 and containing from about 20% to about 80% by volume of an organic diluent selected from the group consisting of acetone, acetonitrile, and a combination of acetone and acetonitrile.

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