Surfactant compositions and methods for clarifying and...

G - Physics – 01 – N

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150/1

G01N 33/50 (2006.01)

Patent

CA 1237966

SURFACTANT COMPOSITIONS AND METHODS FOR CLARIFYING AND PARTITIONING AQUEOUS LIPID-CONTAINING SPECIMENS ABSTRACT Compositions and methods are provided for clarifying and partitioning aqueous lipi-containing specimens or samples such as lipemic serum and plasma. The compositions contain zwitterionic surfactant and water-immiscible organic solvent for lipids. The components of the compositions are selected such that they are compatible in vitro and, when constituted with aqueous specimens, do not interfere with biological or chemical activity of endogenous and exogenous analytes present in the respective specimens. The methods serve to partition the specimens into discrete aqueous and non- aqueous phases. The phases in turn call be individually assayed with respect to any of various analytes, for diagnostic or other purposes.

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