Recombinant a vipox virus

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

167/130, 195/1.2

C12N 15/33 (2006.01) A61K 39/12 (2006.01) C12N 7/01 (2006.01) C12N 15/63 (2006.01) C12N 15/79 (2006.01)

Patent

CA 1341403

The present invention provides a method for inducing an immunological response in a vertebrate to a pathogen by inoculating the vertebrate with a synthetic recombinant avipox virus modified by the presence, in a non-essential region of the avipox genome, of DNA from any source which encodes for and expresses, an antigen of the pathogen. The present invention further provides a synthetic recombinant avipox virus modified by the insertion therein of DNA from any source, and particularly from a non-avipox source, into a non-essential region of the avipox genome.

575793

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