Process for the enzymatic resolution of the optical isomers...

Details Process for the enzymatic resolution of the optical isomers... Process for the enzymatic resolution of the optical isomers...

C - Chemistry, Metallurgy

12

P

195/65, 195/86

C12P 41/00 (2006.01) C12N 11/00 (2006.01) C12P 7/62 (2006.01) C12P 11/00 (2006.01)

Patent

CA 1319635

Abstract A process is disclosed for the biotechnological resolution by means of stereoselective enzymatic thio- transesterification of the racemic mixture of the optical isomers of the compounds of formula (I): Image (I) wherein R, R' and R", which can be either equal to, or different from, one another, represent a linear alkyl group of from C1 to C4, in the presence of an enzyme capable of selectively causing the reaction of thio-transesterification of the (L)-isomer to take place, with the (D)-isomer being kept substantially unchanged, and being then separated by means of known techniques.

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