Method of assaying myosin light chain

Details Method of assaying myosin light chain Method of assaying myosin light chain

G - Physics

01

N

167/37, 195/1.11

G01N 33/68 (2006.01) C07K 16/18 (2006.01) G01N 33/543 (2006.01) G01N 33/577 (2006.01)

Patent

CA 1289870

ABSTRACT OF THE DISCLOSURE The present invention provides a method of assaying immunologically myosin light chains in a human serum sample, which comprises using as an antibody reagent a monoclonal antibody having specificity to the myosin light chain which recognizes the common antigenic determinant of the myosin light chain in the human serum and the myosin light chain of at least one of xenogeneic animals and using as an antigen reagent the myosin light chain of a xenogeneic animal to which said monoclonal antibody can be bound. This method has, for the first time, made possible the establishment of a practical method of diagnosing patients with muscle diseases such as myocardial infarction by immunological assay of myosin light chains.

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