Cycloalkylamides of (8b)-1alkyl-6 (substituted)ergolines

Details Cycloalkylamides of (8b)-1alkyl-6 (substituted)ergolines Cycloalkylamides of (8b)-1alkyl-6 (substituted)ergolines

C - Chemistry, Metallurgy

07

D

167/227, 260/206

C07D 457/06 (2006.01) A61K 31/48 (2006.01)

Patent

CA 1339661

This invention provides (8.beta.)-N-cycloalkyl-1-alkyl-6-(substituted)ergoline-8-carboxamides useful for blocking 5HT2 receptors in mammals having an excess of serotonin centrally or peripherally. The invention also provides methods for treating sexual dysfunction, hypertension, migraine, vasospasm, thrombosis, ischemia, depression, anxiety, sleep disorders and appetite disorders with a compound of the invention.

569291

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