1a 7-substituted derivatives of mitomycin and uses thereof

C - Chemistry – Metallurgy – 07 – H

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C07H 15/26 (2006.01) A61K 31/70 (2006.01)

Patent

CA 1292470

ABSTRACT OF THE DISCLOSURE This invention discloses la- and 7-substituted derivatives of mitosanes containing thiocarbamoyl and glycosyl residues. The compounds possess antibacter- ial and antitumor activity, with a concomitant reduc- tion in bone marrow toxicity as compared to the parent compounds.

534836

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