Continuous bio-reactor (heterogeneous catalysis) especially...

C - Chemistry – Metallurgy – 12 – P

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195/141, 195/86

C12P 17/02 (2006.01) C12P 7/00 (2006.01)

Patent

CA 1175766

ABSTRACT OF THE DISCLOSURE process and equipment for advancing the oxida- tion state of a gaseous oxidizable organic substrate through contact with oxygen and a solid state biocatalyst. The process comprises passing through a stationary cata- lytic bed comprising moist, resting cells exhibiting oxy- genase activity, a gaseous, oxidizable organic substrate and a gaseous source of oxygen, until the oxidative state of at least a portion of said substrate is increased, while maintaining the relative humidity in said bed at such a level that said cells remain moist and viable, and while maintaining the temperature is in the vapor state. The process uses an oxygenase enzyme as a catalyst, for the incorporation of molecular oxygen directly into a specific organic molecule, The invention is of particular interest for the conversion of propylene to propylene oxide, and similar reactions that are catalyzed by mono-oxygenase en- zymes.

397521

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