Preparation of pharmaceutical grade amino acid chelates

Details Preparation of pharmaceutical grade amino acid chelates Preparation of pharmaceutical grade amino acid chelates

C - Chemistry, Metallurgy

07

K

260/425, 204/43,

C07K 5/04 (2006.01) C07C 51/41 (2006.01) C07F 15/02 (2006.01)

Patent

CA 1299812

ABSTRACT OF THE DISCLOSURE Pharmaceutical grade amino acid chelates, free of interfering anions, are made by reacting an amino acid ligand with a metal member selected from the group consisting of elemental metals, metal oxides, metal hydroxides and metal carbonates in an aqueous environment wherein the ligand to metal mole ratio is at least 2:1 and recovering the amino acid chelate from said aqueous environment by means of spray or drum drying. The reaction may be carried out in the presence of non-interfering anions such as anions from citric acid, ascorbic acid, acetic acid, carbonic acid and ammonium and alkali metal salts thereof.

541185

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