1-(aminoalkyl) -.alpha., .alpha.-diaryl pyrrolidine-,...

Details 1-(aminoalkyl) -.alpha., .alpha.-diaryl pyrrolidine-,... 1-(aminoalkyl) -.alpha., .alpha.-diaryl pyrrolidine-,...

C - Chemistry, Metallurgy

07

D

167/208, 260/277

C07D 207/09 (2006.01) C07D 207/08 (2006.01) C07D 211/28 (2006.01) C07D 211/34 (2006.01) C07D 223/04 (2006.01) C07D 401/06 (2006.01)

Patent

CA 1246564

ABSTRACT OF THE DISCLOSURE Novel compounds having the formula Image wherein; n is 0, 1 or 2; Ar1 and Ar2 are 2, 3 or 4-pyrido, phenyl or substituted phenyl; Y is aminocarbonyl or cyano; x is 2-5; R is H or loweralkyl; R1 and R2 are hydrogen, cycloalkyl, loweralkyl, or R2 and R3 taken together with the adjacent nitrogen form a heterocyclic residue and diastereoisomers when possible and pharmaceutical salts; are useful for treating cardiac arrhythmias therewith are disclosed.

493339

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