Process for the preparation of a furan derivative

Details Process for the preparation of a furan derivative Process for the preparation of a furan derivative

C - Chemistry, Metallurgy

07

D

260/367.3

C07D 307/52 (2006.01)

Patent

CA 1237440

ABSTRACT Process for the Preparation of a Furan Derivative Ranitidine is prepared by treating the compound (II) Image (II) in which R represents H or preferably methyl with a methylating agent such as a methyl halide, dimethyl sulphate or a methyl sulphonic ester. The reaction may be carried out in the presence of a base or an alkali metal methylsulphinylmethide salt. The starting material (II) is readily obtainable in pure crystalline form and the process does not involve evolution of thiol.

491180

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