Peptides having strong lh-rh/fsh-rh activity and process for...

Details Peptides having strong lh-rh/fsh-rh activity and process for... Peptides having strong lh-rh/fsh-rh activity and process for...

C - Chemistry, Metallurgy

07

K

530/7.2

C07K 7/23 (2006.01) C07K 5/103 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1069888

PEPTIDES HAVING STRONG LH-RH/FSH-RH ACTIVITY AND PROCESS FOR THEIR MANUFACTURE Abstract of the disclosure: The present invention relates to peptides having strong LH-RH/ FSH-RH activity, wherein Gly in 6-position is replaced by different substituted amino acids and in 10-position there is Glycinamide or glycin in 10-position is replaced by a NH-alkyl group with 1 - 3 carbon atoms or a NH-cyclopropyl group. The invention relates as well to a process for manufacturing said peptides, and to pharmaceutical preparations containing said peptides.

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