Process for the preparation of 3,5-disubstituted isoxazoles

C - Chemistry – Metallurgy – 07 – D

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260/311.9

C07D 261/10 (2006.01) C07D 261/12 (2006.01) C07D 261/18 (2006.01)

Patent

CA 1258860

"Process for the preparation of 3,5-disubstituted isoxazoles" ************** ABSTRACT Preparation of 3,5-disubstituted isoxazoles by reacting dichloro- or dibromoformaldoxime with an 1-alkyne derivative optionally followed by the conversion in accordance with conven- tional techniques of the substituents at 3- and 5-position. The 3,5-disubstituted isoxazoles are useful in various fields such as the pharmaceutical and agricultural field and also as intermediates.

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