C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/264.1
C07D 237/10 (2006.01) C07D 405/12 (2006.01)
Patent
CA 1202628
Abstract of the Disclosure A hydrazinopyridazine compound represented by the formula (I) Image wherein R1 represents a hydrogen atom, a halogen atom, a hydroxyl group, a cyano group, a lower alkyl group which may optionally be substituted by a halogen atom or a hydroxyl, lower alkoxy, lower alkylthio, lower alkanoylamino, allyloxy or tetrahydrofurfuryloxy group, a lower alkoxy group which may optionally be substituted by a 2-furyl, phenyl or lower alkoxy group, a lower alkenyl group, a lower alkenyloxy group, or a lower alkynyl group; R2 represents a hydrogen atom, a halogen atom, a cyano group, a lower alkyl group which may optionally be substituted by a halogen atom or a lower alkoxy group, a lower alkoxy group, a lower alkenyl group, or a lower alkenyloxy group; R3, R4 and R5, inde- pendently from each other, represent a hydrogen atom, a halogen atom, a lower alkyl group which may optionally be substituted by a lower alkoxy group, or a lower alkoxy group; R6 and R7, independently from each other, represent a hydrogen atom or a methyl group; Y represents -NH2, -NH-COOC2H5, or Image ; Z represents -O-, -S-, or Image in which R8 represents a hydrogen atom or a lower alkyl group; and n is 1 or 2, or its salt; a process for the production the aforesaid compounds; and use of such compounds as antihypertensive agents.
405400
Himori Norio
Ishimori Tsutomu
Izumi Akihiro
Ohuchi Rikio
Ohuyabu Hiroshi
Smart & Biggar
Teikoku Hormone Mfg. Co. Ltd.
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