Pyrrolidinylamide ester derivative having anti-prolyl...

Details Pyrrolidinylamide ester derivative having anti-prolyl... Pyrrolidinylamide ester derivative having anti-prolyl...

C - Chemistry, Metallurgy

07

D

167/233, 260/325

C07D 295/192 (2006.01) A61K 31/40 (2006.01)

Patent

CA 1280428

NOVEL PYRROLIDINYLAMIDE ESTER DERIVATIVE HAVING ANTI-PROLYL ENDOPEPTIDASE ACTIVITY AND SYNTHESIS AND USE THEREOF Abstract A novel pyrrolidinylamide ester derivative that exhibits inhibitory activity against prolyl endopeptidase, methods for synthesis thereof and its use as an inhibitor against said enzyme are disclosed. The pyrrolidinylamide ester of the invention has the following general formula: Image wherein n is o or an lnteger or 1 to 7 and R is hydrogen atom or a straight or branched alkyl having 1 to 8 carbon atoms.

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