Valiolamine derivatives and production thereof

C - Chemistry – Metallurgy – 07 – H

Patent

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195/101, 167/180

C07H 15/224 (2006.01) A61K 31/70 (2006.01) C07C 215/26 (2006.01) C12P 19/46 (2006.01)

Patent

CA 1289904

Abstract of the Disclosure A novel valiolamine derivative of the formula (I): ( I ) Image where R stands for hydrogen or .beta.-D-glucopyranosyl group is useful for a starting material of valiolamine which can be converted to more potent .alpha.-glucosidase inhibiting compounds. The valiolamine derivative is obtained by cultivating Streptomyces hygroscopics in a culture medium and recovering the valiolamine derivative produced and accumulated from the culture broth.

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