Synthesis of dioxabicylo (3.2.1)octanes and oxepanes

Details Synthesis of dioxabicylo (3.2.1)octanes and oxepanes Synthesis of dioxabicylo (3.2.1)octanes and oxepanes

C - Chemistry, Metallurgy

07

D

260/354.1

C07D 493/08 (2006.01)

Patent

CA 1180340

Synthesis of Dioxabicyclo[3.2.1]Octanes and Oxepanes ABSTRACT The synthesis of C-4 alkyl analogs of racemic (1RS,4SR,5RS)-4-(4,8-dimethyl-5-hydroxy-7-nonenyl)-4- methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid and the corresponding (1RS,4RS,5RS)- derivative is described. The dioxabicyclo[3.2.1]octanes are useful as contragestational agents. The intermediate oxepane analogs are useful as intermediates in the preparation of the contragestational agent zoapatanol.

442914

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